RecruitingNot ApplicableNCT05321745

Fecal Microbiota Transplantation in Pediatric Crohn's Disease

Repeated and Periodic Fecal Microbiota Transplantation in Children With Active and Refractory Crohn's Disease


Sponsor

Biao Zou

Enrollment

40 participants

Start Date

Mar 22, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This study will test the safety and effectiveness of fecal microbiota transplantation (FMT) plus partial enteral nutrition (PEN) in refractory pediatric Crohn's disease (CD) who have failed conventional treatment


Eligibility

Min Age: 2 YearsMax Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This study tests fecal microbiota transplantation (FMT) — transferring healthy gut bacteria from a donor into a patient — as a treatment for pediatric Crohn's disease, a chronic inflammatory bowel condition. **You may be eligible if...** - You are a child or adolescent with a diagnosis of Crohn's disease - Your disease is active and not fully controlled by current medications - You and your parents or guardians consent to participate **You may NOT be eligible if...** - You have severe infections or immunodeficiency - You recently had bowel surgery - You are on antibiotics that cannot be paused Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERStandardized FMT

Fecal microbiota transplantation of fresh bacteria from healthy donor to the whole colon


Locations(1)

Tongji Hospital

Wuhan, Hubei, China

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NCT05321745


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