RecruitingNot ApplicableNCT05325424
The Effect of Laparoscopic Splenectomy on Liver Reserve Function for Cirrhosis Patients
Sponsor
Northern Jiangsu People's Hospital
Enrollment
20 participants
Start Date
Mar 1, 2022
Study Type
INTERVENTIONAL
Conditions
Summary
In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.
Eligibility
Min Age: 18 Years
Inclusion Criteria3
- A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
- Splenomegaly with secondary hypersplenism, Platelet count \< 50\*10\^9/L
- Informed consent to participate in the study
Exclusion Criteria8
- Hepatocellular carcinoma or any other malignancy,
- Child-Pugh grade C
- Recent peptic ulcer disease
- History of Hemorrhagic stroke
- Pregnancy.
- Uncontrolled Hypertension
- Bleeding portal hypertension
- Human immunodeficiency virus (HIV) infection
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Interventions
PROCEDURELaparoscopic splenectomy
The laparoscopic splenectomy was performed by the same surgical team.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05325424
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