Cirrhosis, Liver Clinical Trials

19 recruiting

Frequently Asked Questions

Common questions about Cirrhosis, Liver clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting

Changes in Bile Acids and Microbiota in Patients With Hepatitis D Treated With Bulvertide

Hepatocellular CarcinomaHIV InfectionsCirrhosis, Liver+6 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS20 enrolled1 locationNCT07429864
Recruiting

3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension

Cirrhosis, LiverAdvanced Chronic Liver DiseasePortal Hypertension
Shengjing Hospital150 enrolled1 locationNCT05475015
Recruiting
Phase 2

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States

CirrhosisCirrhosis, LiverCirrhosis Due to Hepatitis B+5 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)256 enrolled13 locationsNCT05832229
Recruiting
Phase 2

Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas With Child-Pugh-B Cirrhosis

Hepatocellular CarcinomaCirrhosis, Liver
The University of Texas Health Science Center at San Antonio32 enrolled1 locationNCT06526104
Recruiting

Intraabdominal Hypertension and Occurrence of Microaspiration in Cirrhotics Under Mechanical Ventilation

Cirrhosis, LiverCritical Illness
University Hospital, Lille226 enrolled2 locationsNCT04530760
Recruiting
Not Applicable

Echocardiography-guided Cirrhosis and Liver Failure-Intensive Care Protocol Sepsis

Cirrhosis, LiverSeptic ShockCirrhotic Cardiomyopathy
Post Graduate Institute of Medical Education and Research, Chandigarh140 enrolled1 locationNCT07286643
Recruiting
Phase 2

EGCG for Hepatocellular Carcinoma Chemoprevention

Cirrhosis, Liver
University of Texas Southwestern Medical Center60 enrolled1 locationNCT06015022
Recruiting
Not Applicable

Cirrhosis Care Alberta (CCAB): A Pragmatic Type II Hybrid Effectiveness Implementation Trial

Cirrhosis, Liver
University of Alberta3,975 enrolled1 locationNCT04149223
Recruiting
Not Applicable

CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

Hepatocellular CarcinomaCirrhosis, Liver
Northern Jiangsu People's Hospital5 enrolled1 locationNCT05433467
Recruiting
Not Applicable

Carvedilol + Simvastatin vs. Carvedilol Alone for Cirrhosis and Cirrhotic Cardiomyopathy and Impact on Hepatic Decompensation and Survival

Acute Kidney InjuryCirrhosis, LiverCirrhotic Cardiomyopathy+2 more
Post Graduate Institute of Medical Education and Research, Chandigarh260 enrolled1 locationNCT06431919
Recruiting
Not Applicable

The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients

Cirrhosis, LiverPortal HypertensionSplenectomy; Status
Northern Jiangsu People's Hospital20 enrolled1 locationNCT05325437
Recruiting

CHronic Hepatopathies Associated with ALcohol Consumption and MetAbolic Syndrome

Hepatocellular CarcinomaNon-Alcoholic Fatty Liver DiseaseNon Alcoholic Steatohepatitis+2 more
Institut National de la Santé Et de la Recherche Médicale, France710 enrolled1 locationNCT05623150
Recruiting
Phase 4

Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose

Liver DiseasesCirrhosis, LiverPortal Hypertension+2 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)238 enrolled6 locationsNCT04073290
Recruiting

SGLT-2 Inhibitors in the Treatment of Ascites

Cirrhosis, LiverDiabete Type 2Ascites Hepatic
University of Palermo40 enrolled2 locationsNCT05999773
Recruiting

Find HDV and Determine Its Status in Turkey

Hepatocellular CarcinomaCirrhosis, LiverFibrosis, Liver+2 more
Yaşar Bayındır, MD20,000 enrolled2 locationsNCT06248580
Recruiting
Phase 2

Liver Cancer Disparities in American Indian and Alaska Native Persons

Hepatocellular CarcinomaHepatitis BCirrhosis, Liver
University of Washington200 enrolled1 locationNCT05304234
Recruiting

Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC)

Cirrhosis, LiverHCCHBV+2 more
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis60 enrolled1 locationNCT05781568
Recruiting
Phase 4

Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial.

Cirrhosis, LiverPortal HypertensionVariceal Hemorrhage+1 more
King's College Hospital NHS Trust1,200 enrolled1 locationNCT05872698
Recruiting

Digitalized Surveillance Management for Liver Cancer Risk Population in Improving Eearly Diagnosis Efficancy in Chinese Population (dSEARCH)

Carcinoma, HepatocellularNon-Alcoholic Fatty Liver DiseaseCirrhosis, Liver+2 more
Ruijin Hospital20,000 enrolled1 locationNCT05870969