Cirrhosis, Liver Clinical Trials

52 recruitingLast updated: June 18, 2026

There are 52 actively recruiting cirrhosis, liver clinical trials across 16 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4. Top locations include Cleveland, Ohio, United States, Yangzhou, Jiangsu, China, San Antonio, Texas, United States. Updated daily from ClinicalTrials.gov.


Cirrhosis, Liver Trials at a Glance

52 actively recruiting trials for cirrhosis, liver are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Not Applicable with 19 trials, with the heaviest enrollment activity in Cleveland, Yangzhou, and San Antonio. Lead sponsors running cirrhosis, liver studies include Northern Jiangsu People's Hospital, Post Graduate Institute of Medical Education and Research, Chandigarh, and The Cleveland Clinic.

Browse cirrhosis, liver trials by phase

Treatments under study

About Cirrhosis, Liver Clinical Trials

Looking for clinical trials for Cirrhosis, Liver? There are currently 52 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cirrhosis, Liver trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cirrhosis, Liver clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 52 trials

Recruiting
Phase 2

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States

CirrhosisCirrhosis, LiverCirrhosis Due to Hepatitis B+5 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)256 enrolled13 locationsNCT05832229
Recruiting
Not Applicable

Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease

Physical InactivityCirrhosis, LiverMuscle Loss+2 more
University of Pennsylvania110 enrolled2 locationsNCT06136221
Recruiting

Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant

Cirrhosis, LiverDiabetes Mellitus RiskTransplant-Related Disorder+1 more
University of Chicago60 enrolled1 locationNCT06950788
Recruiting

CHronic Hepatopathies Associated With ALcohol Consumption aNd metAbolic Syndrome

Hepatocellular CarcinomaNon-Alcoholic Fatty Liver DiseaseNon Alcoholic Steatohepatitis+2 more
Institut National de la Santé Et de la Recherche Médicale, France710 enrolled1 locationNCT05623150
Recruiting

Development of 4D Flow MRI for Risk Stratification of Variceal Bleeding in Cirrhosis

Cirrhosis, LiverGastroesophageal VaricesFontan Procedure
University of Wisconsin, Madison146 enrolled1 locationNCT04867954
Recruiting
Not Applicable

Online Prehabilitation for Patients Awaiting Liver Transplantation

Liver Transplant SurgeryCirrhosis, LiverLiver Disease
University of Alberta177 enrolled6 locationsNCT05899231
Recruiting
Not Applicable

Initial Resuscitation for Acute Kidney Injury in Cirrhosis

hepatorenal syndromeAcute Kidney InjuryCirrhosis, Liver
Massachusetts General Hospital50 enrolled1 locationNCT06525623
Recruiting
Not Applicable

Transitional Care Program for Fluid Overload in Cirrhosis

Cirrhosis, Liver
Milton S. Hershey Medical Center20 enrolled1 locationNCT06174272
Recruiting

Changes in Bile Acids and Microbiota in Patients With Hepatitis D Treated With Bulvertide

Hepatocellular CarcinomaHIV InfectionsCirrhosis, Liver+6 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS20 enrolled1 locationNCT07429864
Recruiting

3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension

Cirrhosis, LiverAdvanced Chronic Liver DiseasePortal Hypertension
Shengjing Hospital150 enrolled1 locationNCT05475015
Recruiting
Phase 1Phase 2

RTX001 Autologous Engineered Macrophages for Liver Cirrhosis

Liver DiseasesCirrhosis, LiverDecompensated Liver Cirrhosis+5 more
Resolution Therapeutics Limited30 enrolled14 locationsNCT06823713
Recruiting

Diagnosis of Lymphohistiocytic Hemophagocytosis in Intensive Care

Cirrhosis, LiverHepatic Insufficiency
University Hospital, Strasbourg, France100 enrolled1 locationNCT07343037
Recruiting
Phase 2

Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas With Child-Pugh-B Cirrhosis

Hepatocellular CarcinomaCirrhosis, Liver
The University of Texas Health Science Center at San Antonio32 enrolled1 locationNCT06526104
Recruiting

Intraabdominal Hypertension and Occurrence of Microaspiration in Cirrhotics Under Mechanical Ventilation

Cirrhosis, LiverCritical Illness
University Hospital, Lille226 enrolled2 locationsNCT04530760
Recruiting
Not Applicable

Echocardiography-guided Cirrhosis and Liver Failure-Intensive Care Protocol Sepsis

Cirrhosis, LiverSeptic ShockCirrhotic Cardiomyopathy
Post Graduate Institute of Medical Education and Research, Chandigarh140 enrolled1 locationNCT07286643
Recruiting
Not Applicable

HMB Enriched Amino Acids to Reverse Muscle Loss in Cirrhosis

Cirrhosis, Liver
The Cleveland Clinic24 enrolled1 locationNCT05166499
Recruiting
Not Applicable

Molecular Mechanism of Exercise in Cirrhosis

Cirrhosis, Liver
The Cleveland Clinic40 enrolled1 locationNCT05982769
Recruiting
Phase 1

A Study of SIPLIZUMAB in AILD and LT Patients

Autoimmune HepatitisCirrhosis, LiverPrimary Sclerosing Cholangitis+3 more
Elizabeth C. Verna8 enrolled1 locationNCT06455280
Recruiting
Phase 1

The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial

Liver DiseasesCirrhosis, LiverLiver Failure
University of Chicago24 enrolled1 locationNCT06871111
Recruiting
Not Applicable

Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis

Cirrhosis, Liver
The Cleveland Clinic32 enrolled1 locationNCT03208868