RecruitingNCT05328765

A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

ACTION HIV (Anal Cancer TherapIes and Outcomes iNitiative for Patients Living With and Without HIV): A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection


Sponsor

Latin American Cooperative Oncology Group

Enrollment

300 participants

Start Date

Jun 9, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Due to the scarcity of data on prognostic and predictive influence on CCA, epidemiological studies evaluating these factors need to be developed in patients with CCA. Therefore, the investigators want to evaluate the profile of patients in the real world and from various parts of the world, describing prognostic factors such as CD4 dosage, time of HIV infection, evaluation of viral load, diagnosis of AIDS, geographic region of diagnosis and treatment, clinical staging, medications concomitant with QRT (risk of drug interactions), comorbidities (possible impact on dose-intensity), use of HAART, time of use of HAART, radiotherapy modality (conventional 3D vs Modulated Beam Intensity \[IMRT\], response to Nigro vs CTII regimens, as well as comparing clinical outcomes with patients without HIV infection.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is a global registry study collecting information on patients with anal canal squamous cell carcinoma, including those with and without HIV, to better understand treatments and outcomes worldwide. **You may be eligible if...** - You are 18 or older - You have a confirmed diagnosis of anal canal squamous cell carcinoma - You have had an HIV blood test - Your cancer can be at any clinical stage **You may NOT be eligible if...** - Complete treatment and outcome data are not available for your case Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

A.C. Camargo Cancer Center

São Paulo, Brazil

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NCT05328765


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