Anal Squamous Cell Carcinoma Clinical Trials

7 recruiting

Anal Squamous Cell Carcinoma Trials at a Glance

13 actively recruiting trials for anal squamous cell carcinoma are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Phase 2 with 5 trials, with the heaviest enrollment activity in New York, Chicago, and Atlanta. Lead sponsors running anal squamous cell carcinoma studies include Christian Hinrichs, Dr. Danielle Vicus, and Columbia University.

Browse anal squamous cell carcinoma trials by phase

Treatments under study

About Anal Squamous Cell Carcinoma Clinical Trials

Looking for clinical trials for Anal Squamous Cell Carcinoma? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Anal Squamous Cell Carcinoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Anal Squamous Cell Carcinoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting
Phase 1

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

Esophageal Squamous Cell CarcinomaCutaneous Squamous Cell CancerBladder Cancer+8 more
EvolveImmune United, Inc160 enrolled9 locationsNCT07217171
Recruiting
Phase 2

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV InfectionAnal Squamous Cell CarcinomaStage II Rectal Cancer AJCC v8+7 more
National Cancer Institute (NCI)40 enrolled14 locationsNCT04929028
Recruiting
Phase 2

MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach

Anal Squamous Cell Carcinoma
University Health Network, Toronto80 enrolled4 locationsNCT06050707
Recruiting

Detecting HPV DNA in Anal and Cervical Cancers

Cervical CancerAnal CancerHPV-Related Anal Squamous Cell Carcinoma+3 more
University of Chicago20 enrolled2 locationsNCT04857528
Recruiting
Phase 2

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

Cervical CancerMetastatic CancerAnal Cancer+18 more
Christian Hinrichs20 enrolled3 locationsNCT05686226
Recruiting
Phase 1Phase 2

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

Cervical CancerAnal CancerPenile Cancer+14 more
Christian Hinrichs15 enrolled2 locationsNCT05639972
Recruiting
Not Applicable

Adaptive Radiation in Anal Cancer

Anal Squamous Cell Carcinoma
Columbia University20 enrolled1 locationNCT05838391
Recruiting
Phase 2

Dynamic ctDNA Assessment in Cervical and Anal Canal Tumors: Optimizing Follow-up and Clinical Outcomes

HPV-Related Anal Squamous Cell CarcinomaHPV-Related Cervical CarcinomaHPV-Related Carcinoma+2 more
Instituto do Cancer do Estado de São Paulo150 enrolled1 locationNCT06640283
Recruiting
Not Applicable

Screening Strategies Among High-risk Populations for Anal Cancer

NeoplasmsHPV-Related Anal Squamous Cell Carcinoma
Lisa Flowers500 enrolled4 locationsNCT06628570
Recruiting
Not Applicable

Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer.

Cervical CancerAnal CancerVulvar Cancer+4 more
Dr. Danielle Vicus110 enrolled1 locationNCT03061435
Recruiting

A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

HIV InfectionsAnal Squamous Cell Carcinoma
Latin American Cooperative Oncology Group300 enrolled1 locationNCT05328765
Recruiting

High Resolution Anuscopy Study

Anal Squamous Cell CarcinomaHuman Papilloma Virus
Universitair Ziekenhuis Brussel500 enrolled1 locationNCT06697964
Recruiting

Re-optimization Based Online Adaptive Radiotherapy of Anal Cancer

Anal CarcinomaAnal CancerAnal Squamous Cell Carcinoma
Herlev Hospital205 enrolled1 locationNCT05438836