RecruitingPhase 4NCT05347069

Efficacy and Safety of Aspirin in Patients With Chronic Coronary Syndromes Without Revascularization

Sponsor

Takeshi Morimoto

Enrollment

2,890 participants

Start Date

Jun 14, 2022

Study Type

INTERVENTIONAL

Conditions

The purpose of this study is to evaluate the efficacy and safety aspirin in patients with chronic coronary syndromes without revascularization.

Min Age: 20 Years

Patients with chronic coronary syndromes with ≧50% diameter stenosis in one or more major coronary vessels/major branches on coronary CT or coronary angiography but not eligible for coronary revascularization
Patients for whom consent can be obtained

Patients with history of acute coronary syndromes (ACS)
Patients with history of percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG)
Patients with left main trunk stenosis (≥50%)
Patients for whom aspirin administration is mandatory
Patients undergoing antithrombotic therapy other than aspirin
Patients with atrial fibrillation
Patients with history of stroke within six months
Patients scheduled for major surgical procedures that will require aspirin discontinuation
Patients with contraindication of aspirin
Patients expected to have a prognosis of 1 year or less due to comorbidities
Women of child-bearing potential or women who have a positive pregnancy test at enrolment or randomization
Patients who are judged by attending physicians to be inappropriate to participate in this study