RecruitingNCT05363059

Effect of Bariatric Surgery Versus Medical Therapy on Metabolic Syndrome

Army Medical University


Sponsor

Third Military Medical University

Enrollment

200 participants

Start Date

May 1, 2010

Study Type

OBSERVATIONAL

Conditions

Summary

Bariatric surgery (BS) is known to improve the components of metabolic syndrome (MS) in obese patients. However, few studies have evaluated the impact of bariatric surgery versus medical therapy (MT) in patients with MS, especially in patients with low body mass index (BMI). This study aimed to assess the effect of bariatric surgery on MS in patients with low BMI by comparing BS (BMI\<35 kg/m2 and BMI≥35 kg/m2) with MT (BMI\<35 kg/m2). A retrospective study including patients with MS undergoing bariatric surgery and medical therapy at a single institution. We follow up the 5 years effect of bariatric surgery versus medical therapy on the remission of MS, its individual components, atherosclerotic cardiovascular disease (ASCVD) risk, and medication used.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria3

  • BMI<35 kg/m\^2
  • Underwent bariatric surgery or medical therapy
  • Patients met the diagnostic criteria for MS, defined criteria derived from the joint interim statement (JIS)

Exclusion Criteria14

  • Patients who failed to follow up
  • Insulin dependent diabetes
  • congenital dementia
  • brain trauma
  • epileps
  • severe hypoglycemic coma
  • cerebrovascular disease
  • ischemic
  • heart disease
  • renal dysfunction
  • alcohol abuse
  • mental illness
  • psychoactive substance abuse
  • unwillingness to provide informed consent

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Interventions

DRUGHypoglycemic drugs

drug

PROCEDUREBariatric surgery

surgery


Locations(1)

Stryker Laparoscopy

Chongqing, Chongqing Municipality, China

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NCT05363059


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