RecruitingNot ApplicableNCT07574333

Effects of Short and Long Courses of Intermittent Hypoxic-Hyperoxic Training in Patients With Type 2 Diabetes Including Elderly

A Single-Center Randomized Clinical Trial With Prospective Follow-up of the Efficacy and Safety of Short and Long Duration Intermittent Hypoxic-Hyperoxic Training in Patients With Type 2 Diabetes Mellitus Including Elderly Patients

Sponsor

National Medical Research Center for Therapy and Preventive Medicine

Enrollment

250 participants

Start Date

Oct 15, 2025

Study Type

INTERVENTIONAL

Conditions

Metabolic Syndrome Type 2 Diabetes Mellitus (T2DM)Older Adults (65 Years and Older)Hyperglycemia

Summary

This is a single-center randomized controlled trial evaluating the efficacy and safety of short (3 days) versus long (10 days) courses of intermittent hypoxic-hyperoxic training (IHHT) in patients with type 2 diabetes mellitus aged 50-74 years. Participants will be randomized into three groups: 3-day IHHT course (n≥100), 10-day IHHT course (n≥100), or control group receiving gas mixture with constant O2 21% for 10 days (n≥50). The primary outcomes are fasting glucose levels and HbA1c. Secondary outcomes include cardiovascular parameters, quality of life, cognitive function, and biological age.

Eligibility

Min Age: 50 YearsMax Age: 74 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Intermittent Hypoxic-Hyperoxic Training (10 days), Intermittent Hypoxic-Hyperoxic Training (3 days), and others for people with hyperglycemia, metabolic syndrome, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 50 Years to 74 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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