RecruitingNCT05364749

Selective CT for Anticoagulated Head Injured Patients

Selective Neuroimaging for Head-injured Emergency Patients Who Take Anticoagulant Medication


Sponsor

Dr. Kerstin de Wit

Enrollment

4,000 participants

Start Date

Feb 1, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are to: 1. Derive and externally validate a new highly sensitive and maximally specific clinical decision rule for the exclusion of traumatic brain injury in head-injured ED patients who take anticoagulant medications; and, 2. Estimate the sensitivity and specificity of existing head injury clinical decision rules in head-injured ED patients who take anticoagulant medications.


Eligibility

Min Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating whether selective CT scanning (scanning only when clinically appropriate) is safe for patients on blood thinners (anticoagulants) who come to the emergency room after a head injury. The goal is to reduce unnecessary scans while still catching serious injuries. You may be eligible if... - You are 16 years of age or older - You have had a head injury and are presenting to the emergency department - You have had a head CT scan in the emergency department - You are currently taking anticoagulant medications You may NOT be eligible if... - Your head injury happened more than 48 hours before arriving at the emergency department - You have a penetrating head injury - You have been previously enrolled in this study - You live outside the hospital's catchment area - You were transferred from another emergency department after imaging was already done - You leave the emergency department before completing your medical assessment Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(7)

University of British Columbia

Vancouver, British Columbia, Canada

Hamilton Health Sciences Corporation

Hamilton, Ontario, Canada

Kingston Health Sciences Centre

Kingston, Ontario, Canada

Ottawa Hospital Research Institute

Ottawa, Ontario, Canada

Sinai Health

Toronto, Ontario, Canada

Hôpital du Sacré-Cœur de Montréal

Montreal, Quebec, Canada

CHU de Québec - Université Laval

Québec, Quebec, Canada

View Full Details on ClinicalTrials.gov

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NCT05364749


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