Head Injury Clinical Trials

12 recruiting

Head Injury Trials at a Glance

16 actively recruiting trials for head injury are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Atlanta, Bethesda, and Bologna. Lead sponsors running head injury studies include Children's Hospital Medical Center, Cincinnati, Dr. Kerstin de Wit, and Azienda USL Reggio Emilia - IRCCS.

Browse head injury trials by phase

Treatments under study

About Head Injury Clinical Trials

Looking for clinical trials for Head Injury? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Head Injury trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Head Injury clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting

Selective CT for Anticoagulated Head Injured Patients

Traumatic Brain InjuryHead InjuryIntracranial Hemorrhage, Traumatic+1 more
Dr. Kerstin de Wit4,000 enrolled7 locationsNCT05364749
Recruiting
Phase 2

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

DepressionAnxietyDysautonomia+8 more
University of California, Los Angeles75 enrolled1 locationNCT06073886
Recruiting

Treatment and Outcome of Patients With Mild Head Injury

Head Injury Trauma
Azienda USL Reggio Emilia - IRCCS4,500 enrolled4 locationsNCT07339319
Recruiting

Platelet Inhibitor Treated Patients With Head Injury Trauma Meeting NICE Criteria : is the CT-scan Mandatory ?

EmergenciesHead Injury Trauma
Rennes University Hospital3,200 enrolled12 locationsNCT03687528
Recruiting

Healthcare Services for Older People Who Have Fallen With Potential Head Injury

Older Adults (65 Years and Older)FallsHead Injury
Portsmouth Hospitals NHS Trust1,000 enrolled1 locationNCT07111871
Recruiting
Not Applicable

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

InsomniaTraumatic Brain InjuryDepression+7 more
Johns Hopkins University360 enrolled5 locationsNCT05663034
Recruiting
Not Applicable

Biomarker Role in Assessing Imaging Needs for Mild Cranial Trauma

Brain InjuriesHead Injury
Emory University350 enrolled1 locationNCT06932588
Recruiting

Screening Emotions in Adolescents at the Hospital for mTBI

Brain InjuriesBrain Injury Traumatic MildHead Injury Trauma+4 more
University of California, Davis2,592 enrolled6 locationsNCT06370520
Recruiting
Not Applicable

Setting Families on a Positive Path to Recovery After Pediatric TBI: Road-to-Recovery

Traumatic Brain InjuryHead InjuryBrain Edema+3 more
Children's Hospital Medical Center, Cincinnati200 enrolled1 locationNCT05622461
Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+188 more
Sanford Health20,000 enrolled2 locationsNCT01793168
Recruiting
Not Applicable

Osteopathic Manipulative Treatment RCT and Computational Modeling for Head Injuries in Mixed Martial Artists

Head Injury Trauma
New York Institute of Technology100 enrolled1 locationNCT06851234
Recruiting

Characteristics of patients with a head injury that present to a single Australian tertiary emergency department.

Traumatic Brain InjuryConcussionHead Injury
Royal North Shore Hospital280 enrolled1 locationACTRN12621000771853
Recruiting

Does the use of the Canadian CT Head rule (CCHR) definition of minor head injury in a regional NSW emergency department safely lead to lower utilisation of computer tomography (CT) imaging in patients over 65 when compared to the NSW Closed Head Injury guidelines definition?

Mild head injuryminor head trauma
University of New South Wales1,080 enrolled1 locationACTRN12620000887976
Recruiting

Evaluating the effectiveness of a return to work programme for adults living in Waikato receiving a ‘sickness’ benefit.

Traumatic Head InjuryAll health conditions or disabilities that impact on a client's ability to workDepression+3 more
University of Auckland280 enrolled1 locationACTRN12617000517370
Recruiting

The Australia and New Zealand Emergency Department Airway Registry (ANZEDAR). A multi-centre observational study of the practice of intubation in the Emergency Department (ED)

Shock due to traumaAltered mental status not due to overdoseStroke/ICH+12 more
Toby Fogg2,500 enrolled30 locationsACTRN12613001052729
Recruiting

Management of patients with mild head injury in Australian Emergency Departments: The Neurotrauma Evidence Translation (NET) Trial

Mild head injury
National Trauma Research Institute34 enrolled1 locationACTRN12612001286831