Evaluation of Electrode-modiolus Distance and Cochlear Fibrosis Using Depth Sounding and Spectroscopy Tools
Evaluation of Electrode-modiolus Distance and Cochlear Fibrosis Using Depth Sounding and Spectroscopy Tools: Comparison With Postoperative Cone Beam CT
University Hospital, Montpellier
180 participants
Jan 12, 2023
OBSERVATIONAL
Conditions
Summary
Cochlear fibrosis development can compromise the success and the outcomes of the cochlear implantation (CI) thus affecting the quality of life of the implanted patient. Correlating the results of the Transimpedance Matrix (TIM) measurements to the implant electrode location determined by the Cone Beam Computer Tomography (CBCT), this study aims to identify a range of TIM profiles within the implanted population, certain profiles suggesting the growth of the fibrosis tissue in cochlea
Eligibility
Inclusion Criteria12
- Group with long-term implantation:
- Age18 years or older
- Affiliation to the French social security
- Signed and dated informed consent form
- Users of uni or bilateral cochlear implants for more than 6 months (CI24CA, CI422, CI512, CI522, CI532, CI612; CI622; CI632), in primo-implantation or reimplantation, with more than 18 electrodes active
- Postoperation CBCT imaging results available
- Recently-implanted group:
- Age18 years or older
- Affiliation to the French social security
- Signed and dated informed consent form
- Indication for CI622 or CI632 cochlear implants
- Postoperation CBCT imaging results available
Exclusion Criteria3
- Vulnerable individuals (minors, adults protected in accordance to the French Public Health code, patients deprived of liberty by court decision)
- Daily usage of the cochlear implant for less than 4 hours or weekly usage for less than 5 days
- Failure or disfunction of the cochlear implant
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Interventions
TIM measurements are based on cochlear implant back-telemetry function. Each electrode contact is stimulated in monopolar mode. Transimpedance is represented by the ratio between the voltage measured at each recording electrode and the current injected at the stimulation contact. The result of the measurements is a matrix of 21x21 transimpedances. Stimulation current cannot be perceived by a patient thus making TIM measurements a non-invasive and painless procedure. The test duration is only 2-3 minutes
Depth sounding and spectroscopy are based on the matrixes obtained after TIM imaging. Deep sounding measures the capacitances throughout the electrode array whereas spectroscopy determines the phase of every transimpedance value. These tests take 10 to 15 minutes together. The stimulation intensity used by depth sounding technique can be perceived by a patient. If it is considered as unpleasant, the test will be stopped.
CBCT is a routine postoperative assessment after CI, non-invasive and painless for patients.
Locations(1)
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NCT05402969