RecruitingPhase 4NCT05436054

A Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy

A Randomised Controlled Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy

Sponsor

Aalborg University Hospital

Enrollment

400 participants

Start Date

Oct 1, 2022

Study Type

INTERVENTIONAL

Conditions

Colon Disease

Summary

The trial is about comparing the efficacy of Plenvu with Picoprep. Both are bowel cleansing agents prior to visual examination of the large bowel to exclude cancer disease. 400 patients who are referred for colonoscopy to a single center in North Jutland will be randomised either to Picoprep or Plenvu. These patients will then answer a questionnaire prior to colonoscopy. The questionnaire is about the most common expected side effects and the experience of cleansing og intake of the bowel agents. The effect of the two agents will examined using a special scoring system (Harefield) to determine the quality of bowel cleansing. Colonoscopist who evaluate the cleansing is blinded to which agent the patient has taken.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial compares two bowel-cleansing preparations — Plenvu (a low-volume powder drink) and Picoprep (a small-volume laxative) — used before colonoscopy to check for colon cancer and other conditions. Researchers want to know which preparation cleans the bowel more effectively and which patients tolerate better, using a standardized scoring system applied by a physician who doesn't know which preparation was used. You may be eligible if you are over 18 and have been referred for a routine (non-emergency, non-screening) colonoscopy, without severe kidney or heart problems. Participation involves taking one of the two preparations at home before your procedure and completing a short questionnaire about side effects on the day of your colonoscopy. This summary was prepared to help patients understand the study in plain language.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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