RecruitingNot ApplicableNCT05439226

Liver Fat as a Dietary Target of the Chinese Medical Nutrition Therapy (CMNT) Diet for Treating Type 2 Diabetes With Nonalcoholic Fatty Liver Disease


Sponsor

State Key Laboratory of Subhealth Intervention Technology

Enrollment

120 participants

Start Date

Jul 5, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Type 2 diabetes (T2D) represents a serious public health problem. Patients with T2D and non-alcoholic fatty liver disease(NAFLD) demonstrate a poor metabolic profile and increase mortality compared with patients with only NAFLD or T2D. Nutritional intervention is the most basic treatment for T2D. Previous study showed that a Chinese medical nutrition therapy (CMNT) diet, which intermittent use of low-calorie medicinal food, has a glucose-lowering effect in T2D. This study aims to investigate the effect of a Chinese medical nutrition therapy (CMNT) diet accompanied by intermittent energy restriction on reducing liver fat and glycated hemoglobin (HbA1c) in patients with T2D and NAFLD.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a specific dietary program called Chinese Medical Nutrition Therapy (CMNT) in people with type 2 diabetes and fatty liver disease (NAFLD). Researchers want to see if the diet reduces liver fat, improves blood sugar control, and supports overall metabolic health. **You may be eligible if:** - You have been diagnosed with both type 2 diabetes and non-alcoholic fatty liver disease (NAFLD) - You are between 18 and 75 years old - Your weight has been stable for at least 3 months - You are on stable diabetes medication (or not yet medicated) - Your BMI is between 18 and 35 **You may NOT be eligible if:** - You have a known food allergy - You drink alcohol heavily (more than 20g/day for women, 40g/day for men) - You have another liver disease such as hepatitis B or C, autoimmune hepatitis, or cirrhosis - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERCMNT diet

Hypocaloric CMNT diet plan: A diet plan with intermittent use of enriched traditional-Chinese-medicinal-foods CMNT diet


Locations(3)

Physical Examination Center of Gezhouba central hospital of Sinopharm

Yichang, Hubei, China

Hunan Shanshui physical examination center

Changsha, Hunan, China

Jinheyuan Outpatient Department, National Sub-health Intervention Technology Achievement Application Center

Changsha, Hunan, China

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NCT05439226


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