RecruitingNCT05462574

Right Ventricle Lipid in Pulmonary Arterial Hypertension (PAH)

Clinical and Mechanistic Understanding of Right Ventricular Steatosis in Pulmonary Arterial Hypertension (PAH)


Sponsor

Vanderbilt University Medical Center

Enrollment

75 participants

Start Date

Jan 17, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The investigators propose to study the relationship between right ventricle (RV) steatosis and RV function, exercise capacity, and outcomes in humans with pulmonary arterial hypertension (PAH) and to identify potential drivers of lipid accumulation.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using specialized heart imaging (cardiac MRI) to look at fat buildup in the right ventricle — the heart chamber that pumps blood to the lungs — in people with pulmonary arterial hypertension (PAH), a condition that causes dangerously high blood pressure in the lungs. Researchers want to understand how fat affects heart function in PAH. **You may be eligible if...** - You are 18 or older - You have a confirmed diagnosis of PAH (idiopathic, heritable, connective tissue disease-related, or drug/toxin-induced) - Your PAH medications have been stable for at least 3 months **You may NOT be eligible if...** - You cannot have an MRI (e.g., metal implants, pacemaker, severe claustrophobia) - Your PAH is caused by heart or lung disease (e.g., left heart disease, COPD, pulmonary embolism) - Your PAH medications are currently being adjusted Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERNo Intervention

No Intervention


Locations(1)

Vanderbilt University Medical Center

Nashville, Tennessee, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05462574


Related Trials