Estimating Risk of Respiratory Infections Attributable to CFTR Heterozygosity
Estimating the Risk for and Severity of Respiratory Infections Attributable to CFTR Heterozygosity
Philip Polgreen
160 participants
Dec 20, 2021
OBSERVATIONAL
Conditions
Summary
A research team member will brush the inferior surface of the subjects' middle turbinate (nasal cavity) using a cytology brush to obtain the cells needed to perform our functional respiratory assays. An individual trained in phlebotomy will draw one 3 ml lavender top tube of blood to test c-reactive protein, calprotectin, and lactoferrin. They will also draw a 5 ml gold top serum separator tube of blood to test fibroblast growth factor-19. The participant will answer questions from the baseline survey and report their current medications interview-style with the research team member.
Eligibility
Inclusion Criteria4
- Previously tested and shown to be a CF carrier
- English-speaking
- Previously tested and shown to not be a CF carrier or CF patient
- English-speaking
Exclusion Criteria3
- Currently sick with a respiratory infection
- Prisoner Status
- Unable to provide own written, informed consent
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05474430