Ventricular Tachycardia Mechanisms
Ventricular Tachycardia Substrate Mechanisms Revealed by Local Repolarization and Conduction Parameters
Emory University
10 participants
Oct 25, 2022
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to understand why certain hearts have ventricular arrhythmias and help identify areas of the heart that cause arrhythmias. There is still a significant gap in understanding why ventricular arrhythmias occur. This study will examine the electrical properties of the heart tissue to understand how these arrhythmias occur, and hopefully identify areas that might lead to ventricular arrhythmias. The hope is that studying this might be able to improve outcomes during ventricular tachycardia (VT) ablations.
Eligibility
Inclusion Criteria2
- Diagnosis of ischemic cardiomyopathy
- Single or dual chamber implantable cardioverter-defibrillator (ICD)
Exclusion Criteria4
- Non-Ischemic cardiomyopathy
- Contraindication to catheter ablation
- Severe peripheral arterial disease or medical condition that prohibit arterial access
- Ventricular tachycardia (VT) or sudden cardiac arrest (SCA) within 30 days of acute coronary syndrome or within 90 days of coronary revascularization
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Interventions
The EasyMap catheter is a temporary quadripolar catheter for recording monophasic action potentials and for intracardiac pacing. During a standard of care VT ablation, the MAP catheter will be used to study cellular action potential of the ventricular myocardium, which cannot be done on traditional catheters. The catheter is placed on the myocardium (similar to other traditional catheters) and a recording signal is transmitted to the workstation. Using the MAP catheter the will not interrupt or distort any of the standard treatment procedures.
Locations(3)
View Full Details on ClinicalTrials.gov
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NCT05478213