RecruitingNot ApplicableNCT05599022

Randomized Assessment of TcMS for VT Storm

Randomized Assessment of the Efficacy of Transcutaneous Magnetic Stimulation in Patients With Ventricular Tachycardia Storm


Sponsor

University of Pennsylvania

Enrollment

60 participants

Start Date

May 22, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Three-arm randomized clinical trial comparing two strategies of TcMS to sham stimulation in patients with VT storm. The hypothesis of the study is that TcMS will reduce the burden of VT in the 24 hours after randomization compared to sham stimulation and that TcMS with theta burst stimulation (TBS) will be more effective at reducing VT burden than low frequency TcMS.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • ≥3 episodes of sustained VT or appropriate ICD therapies within 24 hours despite the use of at least one antiarrhythmic drug

Exclusion Criteria3

  • Plan for catheter ablation of VT in the next 24 hours
  • Pregnancy
  • Contraindication to TcMS (i.e. implantable ventricular assist device, metal implanted in the head or neck \[except the mouth\], implanted medication pumps, cochlear implant, implanted brain stimulator, ocular implant, history of malignancy in the neck)

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Interventions

DEVICEMagnetic Stimulation

Transcutaneous Magnetic Stimulation


Locations(1)

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

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NCT05599022


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