RecruitingNCT05492708

The Heartland Study

Children's Health in the Heartland Study


Sponsor

Heartland Health Research Alliance

Enrollment

2,600 participants

Start Date

Jan 11, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S.. The objective of the Heartland Study is to address major knowledge gaps concerning the health effects of herbicides on maternal and infant health. The study is being conducted to evaluate the associations between environmental exposures to herbicides during and after pregnancy and reproductive health outcomes. The study is measuring multiple biomarkers of herbicide exposure among pregnant Midwesterners and their partners to evaluate associations with pregnancy and childbirth outcomes, epigenetic biomarkers of exposure, and child development.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria2

  • Pregnant persons ages 18 or older at time of consent who are ≤20+6 weeks pregnant. Best clinical estimate of gestational age will be utilized for recruitment purposes. Enrollment in the first trimester (≤ 13 + 6) is preferred, but anyone ≤ 20 +6 is permitted.
  • Living in one of the 13 Heartland Study region states at the time of enrollment (Arkansas, Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, or Wisconsin) Optional inclusion of the putative biological father

Exclusion Criteria2

  • Participants who are not fluent in and/or do not fully understand, read, write, or speak the English language.
  • Other inability to provide informed consent to participate

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Locations(4)

Indiana University Medical Center

Indianapolis, Indiana, United States

University of Iowa Health Care

Iowa City, Iowa, United States

Gundersen Health

La Crosse, Wisconsin, United States

Marshfield Clinic

Marshfield, Wisconsin, United States

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NCT05492708


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