Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries

This study compares a new wound dressing powder (Transforming Powder Dressing, or TPD) against standard-of-care dressings for treating Stage 2, 3, or 4 pressure injuries (bedsores) in adults. You may be eligible if: - You are between 18 and 85 years old - You have a Stage 2, 3, or 4 pressure injury - Your wound has mild to moderate drainage - Your wound does not have an active infection - You are able to give written consent and follow study visits - You are medically stable You may NOT be eligible if: - You have a known allergy to the study dressing or its ingredients - Your pressure injury is unstageable, deep tissue, or Stage 1 - Your wound is heavily draining - You have an active wound infection - You have poorly controlled diabetes (HbA1c over 12) - Your BMI is above 45 - You have vascular disease or lymphedema in an affected limb - You have severe limb ischemia (ABI below 0.7) - You recently received or will receive immunosuppressants or biologics - You are using concurrent treatments like hyperbaric oxygen or skin substitutes - You have wound necrosis that cannot be removed - You have fistulas, gangrene, or untreated HIV - You are currently pregnant or breastfeeding - You are awaiting an organ transplant Talk to your doctor to see if this trial is right for you.