RecruitingPhase 2NCT06283979

A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.

A Multi-center, Randomized (1:1), Controlled Phase II Trial of STIMULAN VG With Debridement and a Course of Systemic Antibiotics vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.


Sponsor

Biocomposites Ltd

Enrollment

60 participants

Start Date

Jun 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this trial is to assess the safety, tolerability and between-group effect size of STIMULAN VG (with debridement) and a course of systemic antibiotics to standard of care (debridement and systemic antibiotics only) for the treatment of osteomyelitis associated stage IV pressure ulcers.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying STIMULAN VG and a procedure called Standard of Care for people with osteomyelitis and pressure ulcer, stage iv. The study is currently recruiting participants at 9 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

COMBINATION_PRODUCTSTIMULAN VG

Insertion of STIMULAN VG into the ulcer cavity prior to flap/primary closure.

PROCEDUREStandard of Care

Standard of Care. Ulcer bursectomy, debridement and flap/primary closure. Peri-operative antibiotics.


Locations(9)

Advanced Foot Care, LLC

Phoenix, Arizona, United States

Northwestern University Feinberg School of Medicine

Chicago, Illinois, United States

Henry Ford Hospital

Detroit, Michigan, United States

University of Mississippi Medical Center

Jackson, Mississippi, United States

Missouri Orthopaedic Institute

Columbia, Missouri, United States

University of Nebraska Medical Center

Omaha, Nebraska, United States

Rutgers New Jersey Medical School

Newark, New Jersey, United States

NYU Langone Hospital - Long Island Clinical Research Center

Mineola, New York, United States

University of Pittsburgh, McGowan Institute for Regenerative Medicine

Pittsburgh, Pennsylvania, United States

View Full Details on ClinicalTrials.gov

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NCT06283979


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