Targeting Apathy With Music in Parkinson's Disease
The Role of a Personalized Music Intervention Towards Alleviating Apathy in Parkinson's Disease
University of British Columbia
50 participants
Feb 9, 2022
INTERVENTIONAL
Conditions
Summary
Parkinson's Disease (PD) is often accompanied by non-motor symptoms that make treatment more difficult. One such symptom is apathy (lack of motivation and emotion). There are no treatments for apathy in PD, and this remains a major unmet need in PD patients. One possible way to target apathy in PD patients is listening to music, which has been shown to help improve apathy in older adults. Little work has explored the mechanism in which music targets apathy. Thus, the goal of this study is to understand how music listening can impact the brain towards decreasing apathy in PD patients.
Eligibility
Inclusion Criteria1
- \- Clinical diagnosis of Parkinson's Disease following MDS Parkinson's disease criteria
Exclusion Criteria8
- Participants with atypical Parkinsonism (eg. Progressive supranuclear palsy, multiple system atrophy, drug induced, etc.)
- Epilepsy
- Other neurological disease/complications (eg. myopathy, stroke, brain lesion, MS)
- Significant cognitive impairment (MoCa <21)
- Moderate depression (Beck's Depression Inventory >20)
- Severe/multiple head trauma(s)
- Participants with metal/medical implants, including any of the following: artificial heart valve, brain aneurysm clip, electrical stimulators, ear or eye implant, implanted drug infusion pump, coil, catheter, or filter in any blood vessel, orthopedic hardware such as artificial joint, plate, and/or screws, other metallic prostheses, shrapnel, bullets, or other metal fragments, surgery or tattoos, including tattooed eyeliner, in the last six weeks, cardiac pacemaker, wires or defibrillator, or ferromagnetic aneurysm clip)
- Participants who have gone through specific injuries/brain surgery (eg. an injury where a piece of metal lodged in the eye or orbit)
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Interventions
This intervention involves listening to participant-selected music that they have evaluated as rewarding/motivating. YouTube Music will be used to build both personalized music and podcast interventions.
This intervention involves listening to participant-selected podcasts of neutral content. YouTube Music will be used to build both personalized music and podcast interventions.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05505019