Apathy Clinical Trials

16 recruiting

Apathy Trials at a Glance

13 actively recruiting trials for apathy are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Toronto, Berlin, and Bydgoszcz. Lead sponsors running apathy studies include Sunnybrook Health Sciences Centre, Hospital Center Guillaume Régnier, and Anhui Medical University.

Browse apathy trials by phase

Treatments under study

About Apathy Clinical Trials

Looking for clinical trials for Apathy? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Apathy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Apathy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting
Not Applicable

rTMS for Apathy Clinical Trial

DementiaAlzheimer DiseaseMild Cognitive Impairment+3 more
Sunnybrook Health Sciences Centre10 enrolled1 locationNCT05561205
Recruiting

Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression

AnxietyAnhedoniaCognition+5 more
Riccardo Guglielmo100 enrolled5 locationsNCT07146503
Recruiting
Not Applicable

Targeting Apathy With Music in Parkinson's Disease

Parkinson DiseaseApathy
University of British Columbia50 enrolled1 locationNCT05505019
Recruiting

Effects of Personalized Digital Reminiscence Therapy on Patients With Neurocognitive Disorders

Cognitive Impairment, MildApathy in DementiaApathy+2 more
KompanionCare SAS80 enrolled5 locationsNCT07237009
Recruiting
Phase 1Phase 2

Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy

SafetyPARKINSON DISEASE (Disorder)Apathy
Integrative Research Laboratories AB75 enrolled13 locationsNCT07461220
Recruiting
Not Applicable

A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults

LonelinessApathyReminiscence Therapy
Montefiore Medical Center50 enrolled1 locationNCT06919094
Recruiting
Phase 2

Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia

Alzheimer DiseaseAlzheimer DementiaAlzheimer Dementia (AD)+3 more
Sunnybrook Health Sciences Centre12 enrolled1 locationNCT07279740
Recruiting
Not Applicable

Respiratory-gated Transcutaneous Auricular Vagus Nerve Stimulation for Improving Apathy in Parkinson's Disease

Parkinson DiseaseApathyNon-motor Symptoms+1 more
Anhui Medical University60 enrolled1 locationNCT07118956
Recruiting
Phase 1Phase 2

Accelerated rTMS vs. Sham for Stroke Apathy

StrokeMotivationApathy+4 more
Medical University of South Carolina40 enrolled1 locationNCT07113067
Recruiting
Not Applicable

Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics

Major Depressive DisorderApathy
AdventHealth84 enrolled1 locationNCT05877885
Recruiting
Not Applicable

Multidimensional Apathy in Psychiatric Pathologies.

Apathy
University Hospital, Strasbourg, France144 enrolled1 locationNCT04757220
Recruiting

Apathy-related Neurobehavioral Markers of Cognitive Decline in Old-age Bipolar Disorders: Proof-of-concept

Bipolar DisorderApathy
Hospital Center Guillaume Régnier30 enrolled1 locationNCT06914284
Recruiting
Phase 3

Lumateperone for the Improvement of Apathy in Patients With Psychotic Symptoms.

SchizophreniaApathySchizophrenia; Psychosis
Louisiana State University Health Sciences Center Shreveport80 enrolled1 locationNCT06482554