RecruitingNCT05507853

Exploring Central Sensitization in Pregnant Women

In the Joints or in the Brain? Exploring Central Sensitization in Pregnant Women and Its Role in Pain, Physical Activity, Functioning and Health Following Pregnancy


Sponsor

Göteborg University

Enrollment

144 participants

Start Date

Aug 15, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Pelvic Girdle Pain (PGP) is reported by 50% of pregnant women and up to 11 years after pregnancy, 10% of women have persistent and per definition chronic PGP. Central (nervous system) sensitization that elicits pain hypersensitivity, may be one explanation. The overall aim of this study is to explore features of central sensitization in pregnant women and its predictive ability on physical activity, functioning and health in women with PGP. Measurements of central sensitization will be done on two study groups, pregnant women with PGP and healthy controls. To identify women at risk to develop chronic pain in relation to a common pain experience ie PGP in pregnancy, may help us understand if central sensitization early in life explains why women develop chronic pain.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria5

  • pregnant (first time pregnant or previous experience of pregnancy)
  • years of age or older
  • have a single foetus pregnancy
  • be in gestational weeks 20-30
  • able to read and understand Swedish or English

Exclusion Criteria5

  • no history of a fracture or malignant disease in the back, pelvis, pelvic floor or hips
  • no systemic disease of the musculoskeletal or the nervous system
  • no diseases such as gestational diabetes or diabetes type 1 and 2, hypertension
  • no obstetric complications
  • no contradiction for tests.

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Locations(1)

Närhälsan Gibraltargatan

Gothenburg, Sweden

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NCT05507853


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