RecruitingNCT05539677

Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research

Analysis of the Immunogenetic Profile of Patients With Aggressive Course of Malignant Neoplastic Process Resistant to the Standard Treatment Approaches: a Translational Study


Sponsor

N.N. Petrov National Medical Research Center of Oncology

Enrollment

1,000 participants

Start Date

Sep 1, 1998

Study Type

OBSERVATIONAL

Conditions

Summary

The investigators will collect biosamples of patient blood and tumour tissue for further immunological analysis of blood cell subpopulations, immunosupressive factors concentration, HLA expression an lymphocytes and tumour tissue, and and cancer testis antigenes expression on tumour cells, as well as clinical data on patient's stage, therapy, response and demographics. Possible prognostic and predictive dynamic biomarkers will be discovered for individualisation of treatment strategies


Eligibility

Min Age: 1 Year

Plain Language Summary

Simplified for easier understanding

This study is building a biobank and registry — a collection of biological samples and health data — from patients with aggressive solid tumors receiving systemic treatment. The goal is to support future cancer research by providing samples for laboratory analysis, helping scientists better understand how tumors respond to treatment and develop new therapies. **You may be eligible if:** - You have a confirmed solid tumor (cancer confirmed by biopsy) - You are currently receiving systemic therapy (such as chemotherapy, immunotherapy, or targeted therapy) for your cancer - You have archival tumor tissue available - You are willing to provide blood and/or tissue samples **You may NOT be eligible if:** - You have a lymphoma or leukemia (blood cancer) - You have previously had a stem cell or bone marrow transplant - You have a known immune deficiency disorder or are taking immunosuppressive drugs for another condition - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

N.N. Petrov NMRC of Oncology, Oncoimmunology dep.

Saint Petersburg, Russia

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NCT05539677


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