RecruitingEarly Phase 1NCT05549024

68Ga-RM26-RGD PET/CT Imaging in the GRPR and αvβ3 Positive Tumor Patients


Sponsor

Peking Union Medical College Hospital

Enrollment

90 participants

Start Date

Aug 16, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Based on the high expression of specific receptors on the surface of diseased tissues and neovascularization, noninvasive targeted molecular imaging can be used to visualize lesions in vitro by combining specific ligands labeled with short half-life isotopes. In this study, a novel dual-target imaging agent 68Ga-RM26-RGD was used for clinical study of tumor PET/CT imaging to further verify its clinical application value.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This imaging study is testing a new type of PET scan tracer called 68Ga-RM26-RGD in people with breast, brain, or prostate cancer. The tracer is designed to light up tumors on a scan by attaching to specific proteins on cancer cells, potentially helping doctors see cancer more clearly. **You may be eligible if...** - You have confirmed or suspected breast cancer, brain cancer, or prostate cancer - You are able to undergo two PET/CT scans within a 2-week period (one with the new tracer and one with a standard tracer) - You have signed informed consent **You may NOT be eligible if...** - You are pregnant - You are breastfeeding - You have a medical condition that would significantly interfere with the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG68Ga-RM26-RGD

Intravenous injection of 68Ga-RM26-RGD with a dosage of approximately 1.8-2.2 MBq (0.05-0.06 mCi)/ kg.

DRUG18F-FDG

18F-FDG injection

DRUG68Ga-RM26

Intravenous injection of 68Ga-RM26-RGD with a dosage of approximately 1.8-2.2 MBq (0.05-0.06 mCi)/ kg.

DRUG68Ga-RGD

Intravenous injection of 68Ga-RGD with a dosage of approximately 1.8-2.2 MBq (0.05-0.06 mCi)/ kg.


Locations(1)

Peking Union Medical College Hospital

Beijing, China

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NCT05549024


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