RecruitingNCT05554835

Global Registry and Natural History Study for Mitochondrial Disorders

Global Mitochondrial Registry to Define Natural History and Outcome Measures to Achieve Definite Trial Readiness for Mitochondrial Disorders

Sponsor

LMU Klinikum

Enrollment

6,000 participants

Start Date

Feb 1, 2009

Study Type

OBSERVATIONAL

Conditions

MDS NARP Syndrome Leigh Syndrome Mitochondrial Diseases MELAS Syndrome MItochondrial Myopathies Kearns-Sayre Syndrome MIDD SANDO SCAE MERRF Syndrome Coenzyme Q10 Deficiency LHON MNGIE MIRAS Barth Syndrome Pearson Syndrome CPEO

Summary

The main goal of the project is provision of a global registry for mitochondrial disorders to harmonize previous national registries, enable world-wide participation and facilitate natural history studies, definition of outcome measures and conduction of clinical trials.

Eligibility

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with barth syndrome, cpeo, and other related conditions. The study is currently recruiting participants at 18 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Locations(33)

Medical University Innsbruck, Department of Pediatrics

Innsbruck, Austria

Salzburger Landeskliniken, SALK, Paracelsus Medizinische Privatuniversität

Salzburg, Austria

Department of neurology, Klinikum rechts der Isar, Technical University Munich

Munich, Bavaria, Germany

Charité Virchow Klinikum, Klinik für Pädiatrie m. S. Neurologie

Berlin, Germany

Universität Bonn, Klinik und Poliklinik für Neurologie

Bonn, Germany

Universitätsklinikum Köln, Klinik und Poliklinik für Kinder- und Jugendmedizin

Cologne, Germany

Universitätsklinikum Düsseldorf, Klinik für allgemeine Pädiatrie, Neonatologie und Kinderkardiologie

Düsseldorf, Germany

Universitätsklinikum Frankfurt, Klinik für Kinder- und Jugendmedizin, Schwerpunkt Neurologie, Neurometabolik und Prävention

Frankfurt am Main, Germany

University Medical Center Freiburg, Center for children and youth medicine

Freiburg im Breisgau, Germany

Martin-Luther-Universität Halle-Wittenberg, Neurologische Klinik und Poliklinik

Halle, Germany

Universitätsklinikum Hamburg Eppendorf Institut für Humangenetik

Hamburg, Germany

Universitätsklinikum Hamburg Eppendorf, Klinik für Kinder-und Jugendmedizin

Hamburg, Germany

Universitätsklinikum Hamburg Eppendorf, Klinik für Neurologie

Hamburg, Germany

Universitätsklinikum Heidelberg, Zentrum für Kinder- und Jugendmedizin, Sektion für Neuropädiatrie und Stoffwechselmedizin

Heidelberg, Germany

LMU Klinikum, Friedrich-Baur-Institut an der Neurologischen Klinik und Poliklinik

München, Germany

Klinikum am Steinenberg, Kreiskliniken Reutlingen, Klinik für Kinder-und Jugendmedizin, Perinatal- u. Stoffwechselzentrum

Reutlingen, Germany

Universitätsklinikum Tübingen, Neurologische Klinik und Hertie Institut für Klinische Hirnforschung

Tübingen, Germany

Sant'Orsola-Malpighi University Hospital

Bologna, Italy

University of Bologna

Bologna, Italy

University of Bologna

Bologna, Italy

Nemo Clinical Center

Brescia, Italy

University of Cagliari

Cagliari, Italy

AOU Meyer IRCCS Children's Hospital

Florence, Italy

Giannina Gaslini Children's Hospital

Genova, Italy

University Hospital G. Martino

Messina, Italy

IRCCS Foundation Ca' Granda - Ospedale Maggiore

Milan, Italy

IRCCS Foundation Carlo Besta Neurological Institute

Milan, Italy

Department of Clinical and Experimental Medicine, Neurological Institute, University of Pisa & AOUP

Pisa, Italy

IRCCS Foundation Stella Maris

Pisa, Italy

Bambino Gesù Children's Hospital

Rome, Italy

University of Rome

Rome, Italy

AOU City of Health and Science of Turin - Molinette Hospital

Turin, Italy

AOUI Verona

Verona, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05554835

Related Trials

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

NCT018611061 location

A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation (ALLOHA-2)

NCT0547391021 locations

Clinical Trial in Patients With Barth Syndrome- 4TAZPower

NCT075312513 locations

A Phase 1-3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation (ALLOHA-2)

NCT0770257817 locations

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

NCT0645175710 locations