MIDD Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about MIDD clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting

The Head and Neck Registry of the European Reference Network on Rare Adult Solid Cancers

Head and Neck CancerSalivary Gland CancerNasopharynx Cancer+2 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano13,600 enrolled10 locationsNCT05483374
Recruiting
Not Applicable

Middle Cerebral Artery Aneurysm Trial

Middle Cerebral Artery Aneurysm
University of Alberta400 enrolled1 locationNCT05161377
Recruiting
Not Applicable

Impact of an HPV Primary Prevention Intervention on HPV Vaccination Rates Among Adolescents in the AuRA Region.

Middle School and High School Students
Centre Leon Berard1,422 enrolled1 locationNCT07414719
Recruiting

Spectroscopic Evaluation of Middle Ear Infection

Middle Ear Infection
University of California, Irvine150 enrolled2 locationsNCT04812093
Recruiting
Phase 3

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more
Khondrion BV220 enrolled10 locationsNCT06451757
Recruiting
Not Applicable

Deafness and Cognition in Middle-aged Adults

Mild Cognitive Impairment in Middle-aged Adults
Assistance Publique - Hôpitaux de Paris180 enrolled1 locationNCT05149742
Recruiting
Not Applicable

Improving Exercise Adherence With App Technology for At-Risk Adults Living in Rural Kansas and Nebraska

Sedentary Middle Age and Older Aged Adults
Creighton University54 enrolled2 locationsNCT07171255
Recruiting

Evaluation of the Effect of the BOAT® Structured Prevention Program on Violence in Middle Schools

PreventionViolenceStudents+1 more
University Hospital, Montpellier5,400 enrolled1 locationNCT06471413
Recruiting
Not Applicable

Preventing School Exclusion and Opioid Misuse: Effectiveness of the Inclusive Skill-building Learning Approach (ISLA)

Middle SchoolsSchool ExclusionSchool Community+2 more
University of Oregon5,076 enrolled3 locationsNCT06292078
Recruiting

Global Registry and Natural History Study for Mitochondrial Disorders

MDSNARP SyndromeMitochondrial Diseases+11 more
LMU Klinikum6,000 enrolled18 locationsNCT05554835
Recruiting
Not Applicable

A Text- and Audio-based Intervention to Promote Physical Activity in Midlife

Middle Aged
Massachusetts General Hospital30 enrolled1 locationNCT06172933
Recruiting
Not Applicable

Extracranial-intracranial Bypass Surgery for Symptomatic Chronic Middle Cerebral Artery Occlusion: the CMOSS-2 Trial

Symptomatic Chronic Middle Cerebral Artery OcclusionInfarction, Middle Cerebral Artery
Xuanwu Hospital, Beijing420 enrolled1 locationNCT05899582
Recruiting

Investigating the Relationship Between Temporal Bone CT, Bone Density, and Hearing Loss in Otosclerosis Patients

Vitamin D DeficiencyBone DensityOtosclerosis of Middle Ear
İbrahim Emir Yeşil86 enrolled1 locationNCT06830187
Recruiting
Not Applicable

To Assess the Effectiveness and Safety of Catheter-based Focal Intracranial Hypothermia Combined with Endovascular Reperfusion Therapy for Patients with Acute Anterior Circulation Large Artery Occlusion

Acute Ischemic StrokeAcute Cerebrovascular AccidentInternal Carotid Artery+1 more
Guangdong Second Provincial General Hospital262 enrolled1 locationNCT06758609
Recruiting
Not Applicable

Predictive Multimodal MRI Factors in Subacute Cerebral Artery Occlusiontreated by Thrombectomy (PIMISUTT)

Middle Cerebral Artery Acute Ischemic Stroke
Poitiers University Hospital50 enrolled1 locationNCT04651010
Recruiting

AI Recognition of Important Structures in Otolaryngological Surgery

Otolaryngological Diseases Requiring MastoidectomyMiddle Ear Surgery, Endolymphatic Sac Surgery, Cochlear Implant, Labyrinthectomy, Petrous Apex Lesions, Facial Nerve Surgery, and Lateral Skull Base Tumors
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University1,000 enrolled1 locationNCT06726551
Recruiting

Impact of CES1 Genotype on Remimazolam

AdultMiddle AgedElective Surgical Procedures
Korea University Guro Hospital120 enrolled1 locationNCT05841667
Recruiting

Ossiview Normative Mobility Data Collection Protocol

Conductive Hearing Loss, Middle Ear
Audioptics Medical Incorporated120 enrolled1 locationNCT06310278
Recruiting

Translational Immunodiagnostics in Stroke (TrImS)

Atrial FibrillationAcute Ischemic StrokeCardioembolic Stroke+9 more
The University of Hong Kong650 enrolled1 locationNCT05300997
Recruiting
Phase 3Phase 4

Testosterone in Obese Men Trial

Testosterone deficiency in ageing malesObese Middle-Aged and Older Men with Borderline Androgen Deficiency
PHIMR40 enrolled1 locationACTRN12605000283673