RecruitingNot ApplicableNCT05555771

Paediatric Syncope in the Emergency Department

Determining the Effectiveness of Counterpressure Maneuvers in Pediatric Patients Presenting With Syncope to the Emergency Department


Sponsor

Dr. Victoria Claydon

Enrollment

300 participants

Start Date

Sep 3, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators will assess the efficacy of clinically recommended counterpressure maneuvers (CPM) in preventing syncope for paediatric patients. Participants presenting to the emergency department (ED) will first provide written informed consent. In stage I, they will be asked to complete a brief survey documenting the presentation of their syncopal episode, and any prodromal symptoms they experienced. Participants that consent to the second stage of the study will either receive usual care (control arm) or training in counter pressure maneuvers alongside usual care (intervention arm; leg crossing, bending, arm tensing). These patients will be followed for one years time, and will be asked to complete monthly surveys detailing their syncopal and presyncopal recurrence. Medical records will be accessed over the duration of the study to identify any changes in medical diagnosis.


Eligibility

Min Age: 6 YearsMax Age: 18 Years

Inclusion Criteria4

  • Those between the ages of 6-18 years (inclusive)
  • Presenting to the ED daily 1000-2200 with resolved transient loss of consciousness that has occurred within the last week
  • Able to complete the survey in English
  • Willing and able to provide consent and assent

Exclusion Criteria9

  • Those with a known history of any of the following:
  • Suspected or confirmed cardiac arrhythmia diagnosis (e.g., Wolff-Parkinson-White, long QT)
  • Traumatic head injury
  • New presentation of seizure disorder
  • Epilepsy recurrence
  • Overdose, intoxication
  • Structural heart disease
  • Patients with hypoglycaemia and who are psychogenic with vasovagal syncope who do not present with prodromal symptoms
  • Previously enrolled in this study

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Interventions

BEHAVIORALCounterpressure Maneuvers

Movements that can aid in delaying or preventing syncope by recruiting skeletal muscle pumping (via compression of major veins by contracting muscle to eject blood through cardiovascular circuit) and increased sympathetic drive (via sustaining an isometric muscle contraction). In this trial, we will be evaluating three commonly recommended maneuvers of arm tensing, squatting, and leg crossing with arm tensing. Maneuvers should be held for 1-2 minutes, or until symptoms subside.

BEHAVIORALUsual Care

Participants will engage in behavioural interventions and avoidance measures that are commonly recommended as a part of usual care for recurrent syncope. This primarily includes recommendations such as staying hydrated, increasing salt intake, avoiding warm temperatures, avoiding standing for long periods of time, and engaging in regular physical activity. Some patients may be prescribed medication (Midodrine, Fludrocortisone), or other assistive interventions (e.g., compression stockings) at the discretion of their physician.


Locations(1)

BC Children's Hospital

Vancouver, British Columbia, Canada

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NCT05555771


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