RecruitingNot ApplicableNCT04881318

Compression Garments in the Community With POTS


Sponsor

University of Calgary

Enrollment

30 participants

Start Date

May 17, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept compression garment has been demonstrated in an acute laboratory setting. It is not known if commercially available compression garments that participants wear in their every day lives are effective at improving heart rate and reducing symptoms in POTS. This trial will evaluate the use of commercially available waist-high and abdominal compression garments in adults diagnosed with POTS in a community setting.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Inclusion Criteria5

  • Physician diagnosis of Postural Tachycardia Syndrome (POTS)
  • Resident of Canada
  • Owns waist-high compression garment: medical grade or commercially available tights with a pressure rating provided (e.g. 15-18 mmHg, 20-30 mmHg, 30-40 mmHg)
  • Optional Sub-Study: owns an abdominal compression garment (e.g. abdominal shapewear, waist high shorts)
  • Able to participate in a 4-day study (2x2 day segments with a 5-day washout period)

Exclusion Criteria7

  • Overt cause for postural tachycardia (i.e., acute dehydration, thyroid disease) that precludes POTS diagnosis
  • Not a resident of Canada
  • Participants with somatization or severe anxiety symptoms will be excluded
  • Pregnant (self-reported)
  • Inability to tolerate compression garments for the duration of the study
  • Does not own a waist-high compression garment
  • Other factors which in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies

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Interventions

OTHERWaist-High Compression Tights

Waist-high compression tights providing 15-40 mmHg of pressure.

OTHERAbdominal Compression Garments

Abdominal compression garment compressing the abdomen, buttocks, and upper thighs.

DRUGMedications that modulate heart rate and blood pressure

Medications that modulate heart rate and blood pressure that participants regularly take. These medications include beta-blockers, midodrine, ivabradine and stimulants.


Locations(1)

University of Calgary

Calgary, Alberta, Canada

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NCT04881318


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