RecruitingNot ApplicableNCT05570227

Metabolic Phenotypes in Melanoma

Identification of Metabolic Phenotypes Associated With Prognosis and Therapeutic Response in Patients With Melanoma


Sponsor

Peter MacCallum Cancer Centre, Australia

Enrollment

240 participants

Start Date

Jun 27, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This is a single centre, correlative, longitudinal, biomarker study that aims to describe the metabolic features of human melanoma using mass spectrometry.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Patient has provided written informed consent
  • Male or female aged 18 years or older at written informed consent
  • Presence of a known melanoma lesion requiring surgical excision or biopsy
  • Patient is willing and able to comply with the protocol for the duration of the study including undergoing biopsies and receiving a stable isotope infusion (where applicable)

Exclusion Criteria4

  • Patients who meet any of the following criteria will be excluded from receiving a \[U-13C\]Glucose infusion:
  • Diabetes mellitus
  • Pregnancy or breast feeding
  • Patients unable to comply with study procedures and follow up in the opinion of the investigator

Interventions

OTHER[U-13C]Glucose Infusion

Peri-operative infusion of \[U-13C\]glucose


Locations(1)

Peter Mac Callum Cancer Centre

Melbourne, Victoria, Australia

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NCT05570227


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