RecruitingNCT05575024

Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane

Real-time Monitoring of Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy: Propensity Score-matched Comparison Between oXiris and Polysulfone Membranes


Sponsor

Seoul National University Hospital

Enrollment

98 participants

Start Date

Jan 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The new adsorbing membrane for continuous renal replacement therapy (CRRT), oXiris, can reduce plasma cytokines and endotoxins in septic shock patients with severe acute kidney injury, compared with standard membranes. However, its hemodynamic stability or benefits have not been thoroughly evaluated although this is reasonable.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Polysulfone membrane and a medical device called oXiris membrane for people with acute kidney injury due to sepsis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEoXiris membrane

Perform continuous renal replacement therapy with oXiris membrane

DEVICEPolysulfone membrane

Perform continuous renal replacement therapy with polysulfone membrane


Locations(1)

Seoul National University Hospital

Seoul, South Korea

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NCT05575024


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