Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF

This study is looking at how common a type of heart failure called ATTR amyloidosis cardiomyopathy is among patients with heart failure with preserved ejection fraction (HFpEF). HFpEF means the heart pumps normally but is too stiff. ATTR is caused by a protein buildup in the heart and is often underdiagnosed. **You may be eligible if...** - You are 65 or older - You have a confirmed diagnosis of HFpEF (a type of heart failure where the heart's pumping strength is relatively normal) **You may NOT be eligible if...** - You have end-stage kidney disease on dialysis - You have a history of reduced ejection fraction heart failure (below 40%) outside of specific acute events - You had a negative ATTR scan (99mTc-pyrophosphate) within the past year - You have already been diagnosed with amyloidosis - You have severe uncorrected heart valve disease - You cannot lie flat for 15 minutes for the scan Talk to your doctor to see if this trial is right for you.