Heart Failure, Diastolic Clinical Trials

13 recruiting

Frequently Asked Questions

Common questions about Heart Failure, Diastolic clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting
Not Applicable

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Heart FailureHeart Failure, DiastolicCardiorenal Syndrome+5 more
Procyrion320 enrolled47 locationsNCT05677100
Recruiting

Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

Peripheral Arterial DiseaseOverweight and ObesityHeart Failure, Diastolic+1 more
University of Virginia70 enrolled1 locationNCT06009276
Recruiting
Phase 2Phase 3

A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction

Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Not Applicable

Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure

Heart Failure, DiastolicAcute Decompensated Heart FailureHeart Failure, Systolic
University of Health Sciences Lahore320 enrolled1 locationNCT07199088
Recruiting

Prevalence and Risk Factors asSOciated With CArdiac comorbiDIty in psoriAsis

Heart FailureCardiovascular DiseasesStroke+21 more
Herlev and Gentofte Hospital1,000 enrolled1 locationNCT04950218
Recruiting
Not Applicable

Pilot Study Lp299v Supplementation in Chronic Heart Failure

Heart FailureHeart Failure With Reduced Ejection FractionHeart Failure With Preserved Ejection Fraction+2 more
Medical College of Wisconsin20 enrolled1 locationNCT05752760
Recruiting

Multiple-biomarker Approach for Individualized Treatment of Heart Failure with Preserved Ejection Fraction

Chronic Heart FailureHeart Failure With Preserved Ejection FractionHeart Failure, Diastolic
Erasmus Medical Center200 enrolled6 locationsNCT06785506
Recruiting
Not Applicable

Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF

Heart FailureAmyloidosisHeart Failure, Diastolic+1 more
Massachusetts General Hospital515 enrolled1 locationNCT05577819
Recruiting

Value of Intense Phenotyping in Heart Failure With Preserved Ejection Fraction

Heart Failure, Diastolic
University Medical Center Groningen200 enrolled1 locationNCT05479669
Recruiting

Assessment of Left Ventricular Filling Pressure by Applying Artificial Intelligence Algorithms to Left Atrial Speckle-tracking Echocardiography

Heart Failure, DiastolicEchocardiography
Istituto Auxologico Italiano20 enrolled1 locationNCT05768698
Recruiting
Phase 1

Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic
Sardocor Corp.10 enrolled2 locationsNCT06061549
Recruiting

Multimodality Imaging in the Screening, Diagnosis and Risk StratifictiON of HFpEF

Heart Failure, Diastolic
Chinese Academy of Medical Sciences, Fuwai Hospital430 enrolled1 locationNCT04603404
Recruiting

Diagnosis and OutcoMes evaluAtIoN of Multicenter Patients With HFpEF Using Multimodality Imaging

Multicenter StudyHeart Failure, Diastolic
Chinese Academy of Medical Sciences, Fuwai Hospital1,000 enrolled1 locationNCT04602338