RecruitingNCT05586282

Role of Candidate Proteins in Capillary Leakage During Acute Circulatory Failure

Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

380 participants

Start Date

Mar 20, 2023

Study Type

OBSERVATIONAL

Conditions

Cardiogenic Shock Septic Shock Postresuscitation Disease

Summary

* Testing the association between circulating candidate proteins and the level of vascular leakage for three distinct forms of circulatory failure: cardiogenic shock, septic shock, and post-resuscitation syndrome. * Describing immuno-inflammatory profiles associated with massive vascular leakage during those three forms of circulatory failure in humans

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is a research study — not a treatment trial — looking at proteins in the blood that may explain why blood vessels "leak" fluid into surrounding tissues in people experiencing serious circulatory collapse (shock). Understanding this may help develop better treatments for these life-threatening emergencies. **You may be eligible if...** - You are in the hospital experiencing a serious circulatory emergency, such as septic shock (from infection), cardiogenic shock (from heart failure), or post-cardiac arrest syndrome - Your family or legal representative can provide consent, or you can provide it yourself when able **You may NOT be eligible if...** - Consent cannot be obtained from you or a representative - You are not covered by the required health insurance/social security affiliation (in France) - Your condition does not meet the specific definitions of the circulatory failures being studied Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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