Decolonization to Reduce After-Surgery Events of Surgical Site Infection
University of California, Irvine
2,700 participants
Jan 17, 2023
INTERVENTIONAL
Conditions
Summary
The DECREASE SSI Trial (Decolonization to Reduce After-Surgery Events of Surgical Site Infection) is a two-arm multi-center individual placebo-controlled randomized (2,700 participants randomized 1:1) clinical trial to reduce post-discharge surgical site infection following open colon or small bowel surgery by comparing chlorhexidine bathing plus nasal mupirocin in the 30 days following discharge to soap without antiseptic properties (placebo) and placebo nasal ointment. This trial seeks to enhance the care of the 675,000 patients annually who undergo colon and small bowel surgery by finding simple and efficacious interventions to reduce SSI.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Used for daily showering/bathing for 30 days after hospital discharge.
Applied to each nostril twice daily for five days for the first two weeks after hospital discharge.
Used for daily showering/bathing for 30 days after hospital discharge.
Applied to each nostril twice daily for five days for the first two weeks after hospital discharge.
Locations(4)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05586776