RecruitingNCT05605314

Clinical Cohort Study in Patients With Different Subtypes of Primary Sjogren Syndrome Related Dry Eye


Sponsor

Peking University Third Hospital

Enrollment

500 participants

Start Date

Jan 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Primary Sjögren's syndrome is a chronic autoimmune disease that primarily involves exocrine glands, most commonly manifested in dry eye, dry mouth, and in other systems of the body.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria1

  • All enrolled DED participants met the criterion of TFOS DEWS II Definition and Classification Report and pSS-DED group also met 2016ACR/EULAR pSS diagnosis and classification consensus.

Exclusion Criteria1

  • (1) patients were diagnosed as any rheumatic or systematic diseases that would probably affect tear function except for pSS and DED. (2) had a history of ocular trauma or surgery. (3) had a history of wearing contact lens. (4) had concomitant ocular lesions such as acute inflammation or infection, glaucoma or eyelid abnormalities. (5) cannot cooperate properly or finish related examinations.

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Interventions

OTHERCyclosporine

eye drop


Locations(1)

Peking University Third Hospital

Beijing, China

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NCT05605314


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