RecruitingNot ApplicableNCT05609916

CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD


Sponsor

Baylor College of Medicine

Enrollment

200 participants

Start Date

Nov 30, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to examine whether youth with OCD who benefit from CBT augmentation to SRI can discontinue their medication without relapse over 24 weeks.


Eligibility

Min Age: 7 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether adding a targeted form of cognitive behavioral therapy (CBT) to children's existing OCD medication can help them safely reduce or stop taking their medication — offering a path to long-term management without lifelong drug use. **You may be eligible if...** - Your child is between 7 and 17 years old - Your child has a confirmed OCD diagnosis of more than 6 months, with significant symptoms (CY-BOCS score ≥ 16) - Your child has been on a stable, maximum tolerated dose of an SRI medication (like fluoxetine, fluvoxamine, sertraline, citalopram, or escitalopram) for at least 12 weeks and still has persistent symptoms - Both the child and the participating parent are willing to attend study sessions **You may NOT be eligible if...** - Your child is taking paroxetine (due to safety concerns) - Your child has not been on a stable SRI dose for at least 12 weeks - Your child is under 7 or over 17 years old Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCognitive Behavioral Therapy

During Phase I, participants will receive open label (no blinding) CBT during their study participation for 12 to 18 weeks. During Phase II, participants will continue receiving CBT maintenance sessions every two weeks for the first 4 weeks, followed by sessions every four weeks. They will also meet with the study physician every 2 weeks via telepsychiatry appointments for clinical and scalar assessment.


Locations(1)

Baylor College of Medicine

Houston, Texas, United States

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NCT05609916


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