RecruitingNot ApplicableNCT05618626

Prevention of NAFLD and CVD Through Lifestyle Intervention

Cardiovascular Diseases (CVD) and Nonalcoholic Fatty Liver Diseases (NAFLD) Among Gallstone and Cholecystectomy Patients and the Impact of a Novel Diet and Muscle Training Program


Sponsor

Pontificia Universidad Catolica de Chile

Enrollment

300 participants

Start Date

Sep 27, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Prevention of non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD) through lifestyle intervention (MAUCO+) is a clinical trial that aims to improve sarcopenia, aerobic capacity, body composition, and lipid profile, insulin resistance, cardiovascular risk, NAFLD, and maintain a healthier lifestyle. Through the implementation of physical activity and nutritional programs.


Eligibility

Min Age: 45 YearsMax Age: 60 Years

Inclusion Criteria2

  • With and without gallstones disease
  • With various degrees of NAFLD (none too severe)

Exclusion Criteria4

  • Any significant comorbidity or physical limitation to undergo resistance exercise program
  • Use of medications that alter muscle mass (e.g., corticosteroids)
  • History of hepatitis B or C
  • Use of hepatotoxic drugs

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Interventions

OTHERPhysical exercise and dietary intervention for NAFLD

Investigators will assess the efficiency of the intervention by measuring adherence to physical exercise and nutritional diet.


Locations(1)

Centro MAUCO+

Molina, Maule Region, Chile

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NCT05618626


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