RecruitingNCT05890365
Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals
Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals - Extended Validation.
Sponsor
Steno Diabetes Center Copenhagen
Enrollment
300 participants
Start Date
Dec 14, 2023
Study Type
OBSERVATIONAL
Conditions
Summary
The investigators recently demonstrated a increase in liver fat in early middle-aged LBW compared to normal birth weight (NBW) men, and 20% of the LBW - but none of the normal birth weight (NBW) - men had previously unknown non-alcoholic fatty liver disease (NAFLD). Here the investigators will further examine the Increased risk of non-alcoholic fatty liver disease in low birth weight individuals by performing a validation study.
Eligibility
Min Age: 35 YearsMax Age: 40 Years
Inclusion Criteria2
- healthy, men and women born with a low birth weight (birth weight (BW) \<10% of the population) and 50 born with a normal birth weight controls (BW between 50-90% of the population)
- born at term (weeks 39-41)
Exclusion Criteria6
- BMI\>35 kg/m2
- Disease/medication known to affect primary outcome
- Self-reported high physical activity level
- Alcohol intake above general recommendations.
- Metabolic/liver disease
- Weight gain/loss of \>3 kg within the past 6 months
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05890365
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