Wayfinding Intervention and Long-Term Memory
Virtual Reality Interventions to Stimulate Capabilities for Learning and Retrieval of High-Fidelity Memory
University of California, San Francisco
200 participants
Jan 1, 2024
INTERVENTIONAL
Conditions
Summary
Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.
Eligibility
Inclusion Criteria6
- fluent speakers of English
- completed 12 or more years of education
- normal or corrected-to-normal vision
- dexterity to comfortably operate the scanner-compatible response box
- freedom from physical and neurological conditions contra-indicated for fMRI
- must confirm physical stamina and comfort for semi-weekly brisk 30-minute walks on level ground
Exclusion Criteria3
- use of psychotropic medications
- history of concussions or dizziness, vestibular or balance problems
- significant discomfort with virtual reality experiences
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Interventions
Head-mounted display virtual reality game designed to induce environmental enrichment in an adaptive, highly engaging regimen of wayfinding in novel urban and village neighborhoods.
Commercially-available, narrative computer games marketed as cognitively enriching. Can be tablet-based or wireless VR headset-based.
Tablet computer playing Labyrinth spatial wayfinding game in 2.5D
Wireless head-mounted display virtual reality game designed to induce environmental enrichment in an adaptive, engaging regimen of wayfinding in novel urban and village neighborhoods.
Locations(1)
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NCT05625425