CBD for Individuals at Risk for Alzheimer's Disease

This study tests whether cannabidiol (CBD) — a non-psychoactive compound from cannabis — can slow cognitive decline or reduce brain inflammation in older adults with mild cognitive impairment (MCI), a condition that increases the risk of developing Alzheimer's disease. Researchers want to see if CBD has protective effects on brain health. **You may be eligible if...** - You are between 55 and 85 years old - You have been diagnosed with mild cognitive impairment (MCI) by a clinician - You can still function independently in daily life - Your cognitive test scores fall within the MCI range (MoCA score 18–25, CDR score 0.5) **You may NOT be eligible if...** - You have been diagnosed with dementia (not just MCI) - You currently use cannabis or CBD products - You take medications that could interact with CBD (such as certain blood thinners or seizure medications) - You have significant liver disease Talk to your doctor to see if this trial is right for you.