RecruitingNot ApplicableNCT05626426

Electrical Stimulation for the Treatment of Optic Neuropathies

An Open-Label Study to Evaluate the Safety and Efficacy of Repetitive, Transorbital Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies


Sponsor

Stanford University

Enrollment

40 participants

Start Date

Feb 27, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The overall aim of this study is to see whether long-term electrical stimulation with a home-stimulation device works well and is safe for the treatment of open-angle glaucoma. Open-Angle Glaucoma is a disease where the nerves in the back of your eye die off faster than expected regardless of your eye pressure.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a non-invasive electrical stimulation device applied near the eye can slow or improve vision loss in people with glaucoma-related optic nerve damage. Participants use the device at home to receive gentle electrical pulses that may help preserve or stimulate remaining nerve function. **You may be eligible if...** - You are 18 or older with a confirmed diagnosis of glaucoma - You have measurable vision field loss (mean deviation worse than -3 on standard testing) - Your eye pressure is considered stable by your doctor **You may NOT be eligible if...** - You have a history of eye herpes infection - You have a pacemaker or other implanted electrical device - You have significant retinal disease (like diabetic retinopathy or retinitis pigmentosa) - You have corneal opacities, uveitis, or active eye inflammation - You have a brain tumor or incompatible metal implants in the head - You are pregnant or breastfeeding - You have dementia or another condition that would interfere with participation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICERepetitive, Transorbital Alternating Current Stimulation (rtACS)

Patients receive treatment every other day via a headband that delivers electrical stimulation to the retina


Locations(1)

Byers Eye Institute

Palo Alto, California, United States

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NCT05626426


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