RecruitingNot ApplicableNCT05632601

Reexamining Her Cardiovascular Risk - Ottawa WomeN's Longitudinal Cohort Study

Sponsor

Ottawa Heart Institute Research Corporation

Enrollment

210 participants

Start Date

Apr 25, 2023

Study Type

INTERVENTIONAL

Conditions

Cardiovascular Diseases

Summary

The full HER CROWN will be a prospective cohort study to propose a novel, women-specific cardiovascular risk score/ algorithm in the prediction of hard cardiovascular outcomes (myocardial infarction, unstable angina, coronary revascularization, stroke, total and cardiovascular mortality). This future study will be the first longitudinal cohort study, to our knowledge, that is focused entirely on researching the pathophysiology and natural history of cardiovascular disease in women with known female-specific risk factors. Further, the investigators are aiming to recruit a sample that is representative of the ethnic distribution in Canada. The proposed pilot study is a feasibility study as an essential preparatory step for HER CROWN.

Eligibility

Sex: FEMALEMin Age: 25 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This study follows women in Ottawa, Canada who have had certain pregnancy or hormonal complications to track their long-term heart health. Research shows that conditions like pre-eclampsia or gestational diabetes raise a woman's risk of heart disease later in life. **You may be eligible if...** - You are female, between 25 and 55 years old - You are an Ontario resident with a valid health card (OHIP) - You have had or currently have: pre-eclampsia, gestational diabetes, early menopause, primary ovarian insufficiency, or polycystic ovary syndrome (PCOS) **You may NOT be eligible if...** - You do not have any of the qualifying pregnancy or hormonal conditions - You are not an Ontario resident Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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