Contribution From PET-DOPA in Glioblastoma Re-irradiation - A Randomized Phase II Study

This French study investigates whether using a special brain imaging scan called PET-DOPA to guide re-irradiation improves outcomes in patients whose glioblastoma (a type of brain tumor) has come back after initial treatment. **You may be eligible if...** - You are over 18 years old - You have a confirmed glioblastoma (WHO grade IV) that has recurred after prior radiation - You have 1 to 3 recurrence sites, each smaller than 35mm - Your overall health and neurological function are adequate - The recurrence is far enough from critical structures like optic nerves and brainstem **You may NOT be eligible if...** - You cannot have an MRI or PET scan - You have a widespread (diffuse) form of glioblastoma - You are pregnant or breastfeeding - You do not speak French - You are not affiliated with the French social security system Talk to your doctor to see if this trial is right for you.