Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity

This study investigates whether a supervised exercise program can improve brain function and slow cognitive decline in older adults with moderate chronic kidney disease (CKD) who also have mild cognitive impairment. **You may be eligible if...** - You are over 55 years old - You have been diagnosed with stage 3 or 4 chronic kidney disease (reduced kidney function) - You have mild cognitive impairment (score of 18–26 on the MoCA thinking/memory test) - You are able to undergo an MRI scan - You have no history of serious head trauma - You can read, write, and speak English **You may NOT be eligible if...** - You have been diagnosed with dementia (MoCA score below 18) - You already participate in a supervised exercise program 3 or more days per week - You need assistance to walk - You have heart failure (Class III–IV), unstable heart disease, or severe difficulty exercising due to pain or breathlessness Talk to your doctor to see if this trial is right for you.