RecruitingNot ApplicableNCT05658705
Preoperative Supine Time for Adrenal Venous Sampling
Preoperative Supine Time for Adrenal Venous Sampling: A Prospective Randomized Controlled Trial
Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Enrollment
120 participants
Start Date
Mar 29, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
This study aim to understand whether the length of preoperative supine time would affect the AVS outcome.
Eligibility
Min Age: 18 YearsMax Age: 80 Years
Inclusion Criteria3
- Patients are clinically diagnosed as primary aldosteronism with ARR≥37 (PAC showed as pg/ml, renin showed as μIU/mL) and passed through PA confirmatory tests (PAC-post CCT\>110pg/ml, PAC-post SSIT \>80pg/ml, or PAC-post FST\>60pg/ml). PAC: plasma aldosterone concentration;
- Patients with willing for AVS;
- Age 18 or above, male or female, with legal capacity.
Exclusion Criteria11
- Patients with suspected adrenocortical carcinoma or pheochromocytoma;
- Patients with high risk of adrenal surgery;
- Patients have been subtyping to glucocorticoid-suppressible hyperaldosteronism or familial hyperaldosteronism type III;
- Patients were diagnosed as Cushing syndrome or subclinical Cushing syndrome;
- Patients were treated with glucocorticoids recently;
- Patients with whole body or venipuncture area infection;
- Patients with venous access thrombosis;
- Patients are allergic to iodine;
- Patients with X-ray contraindications;
- Patients with coagulation dysfunction;
- Patients are unable to cooperate and follow-up.
Interventions
PROCEDURE15-min supine time
The length of preoperative supine time before AVS was 15 minutes.
PROCEDURE2-hour supine time
The length of preoperative supine time before AVS was 2 hours.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05658705
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