RecruitingNot ApplicableNCT05662280

NIMH K23: Modulation of Frontoparietal Dynamics in Adolescent Working Memory Deficits


Sponsor

Bradley Hospital

Enrollment

40 participants

Start Date

Dec 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Working memory (WM) deficits are a transdiagnostic feature of adolescent psychopathology that substantially contribute to poor clinical and functional outcomes. This proposal will utilize a multimodal neuroscientific approach to investigate whether non-invasive brain stimulation can modulate the neural mechanisms underlying adolescent WM deficits. Directly in line with NIMH priorities, the researchers will identify the contributing roles of prefrontal and parietal regions in WM processes, as well as identify optimal targets and parameters for novel brain-based treatments in adolescent psychopathology. This study is funded by the NIMH-K23


Eligibility

Min Age: 12 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Active Intermittent Theta Burst Stimulation and a medical device called Sham Intermittent Theta Burst Stimulation for people with working memory. The study is currently recruiting participants at 1 location. People eligible for this study include aged 12 Years to 18 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEActive Intermittent Theta Burst Stimulation

Standard iTBS protocol with active coil

DEVICESham Intermittent Theta Burst Stimulation

Standard iTBS protocol with active coil


Locations(1)

E. P. Bradley Hospital

East Providence, Rhode Island, United States

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NCT05662280


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