Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

This study collects blood and tissue samples from people with HIV-related cancers (or HIV-negative people with cancers linked to similar causes) to support ongoing research into why these cancers occur, how they behave, and how they might be better treated. **You may be eligible if...** - You are 18 or older - You are HIV-positive AND have a cancer diagnosis, OR - You are HIV-negative but have been newly diagnosed with or have a recurrence of a cancer that shares biological connections with AIDS-related cancers — such as Kaposi sarcoma, anal cancer, certain lymphomas (Hodgkin's, EBV-positive, plasmablastic), or multicentric Castleman's disease **You may NOT be eligible if...** - You are HIV-positive but cannot provide documentation of your HIV diagnosis or treatment - Your cancer does not fall into the categories linked to HIV/AIDS-related malignancies - You are unwilling to donate samples for research Talk to your doctor to see if this trial is right for you.