Study of Transcranial Direct Current Stimulation to Treat Epilepsy
Pilot Study of Transcranial Direct Current Stimulation (tDCS) to Treat Epilepsy
Mayo Clinic
30 participants
Apr 12, 2023
INTERVENTIONAL
Conditions
Summary
The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.
Eligibility
Inclusion Criteria5
- Clinical diagnosis of generalized onset or focal epilepsy or sleep-related epileptic encephalopathy.
- Estimated to have at least 2 countable seizures per month or spike-wave index ≥50%.
- Has not had control with at least 2 anti-seizure medicines.
- Able to maintain a constant medication for duration of the study (rescue meds allowed).
- Subject or legally authorized representative is able to understand consent and keep a seizure diary in English.
Exclusion Criteria6
- A disease likely to progress over course of the study.
- Psychogenic non-epileptic seizures.
- Suicide attempt or psychiatric hospitalization past 2 years.
- A skin condition interfering with scalp electrodes or allergy to silver.
- Women will verify not pregnant, and if applicable, have a serum pregnancy test.
- Implanted devices (e.g. pacemakers)-except VNS, which is allowed.
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Interventions
Stimulation setting 0.1 mA daily for a 2-month period. Each daily treatment will last for approximately 30 minutes.
Stimulation setting 2.0 mA daily for a 2-month period. A Each daily treatment will last for approximately 30 minutes.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05673915