Feasibility and Clinical Utility of Cell-free DNA (cfDNA) in Identifying Actionable Alterations and Minimal Residual Disease for Lymphoma Patients Across Community Centers in Texas

This study is examining whether a blood test that looks for cancer DNA (called cell-free DNA or liquid biopsy) can help find useful genetic information and detect minimal remaining disease in lymphoma patients treated at community cancer centers in Texas. The goal is to make advanced testing more accessible outside of major academic hospitals. **You may be eligible if...** - You are at least 18 years old - You have been diagnosed with a type of lymphoma called diffuse large B-cell lymphoma that requires treatment - You are willing to provide written consent **You may NOT be eligible if...** - You are pregnant - You have significant cognitive impairment Talk to your doctor to see if this trial is right for you.